摘要
目的:评价拉米夫定治疗对慢性乙型肝炎患者生活质量的影响,分析其主要影响因素。方法:应用健康状况调查问卷(SF-36中文版),对拉米夫定治疗前后50例慢性乙型肝炎患者的生活质量指标进行对照分析,并对其影响因素进行多元线性回归分析。结果:拉米夫定治疗后SF-36总评分及生理功能(PF)、生理职能(RP)、精神健康(MH)、社会职能(SF)、躯体疼痛(BP)和活力(V)的平均评分与治疗前相比有显著差异(P<0.01),影响患者生活质量的主要因素是患病时间及愈后。结论:拉米夫定治疗能改善慢性乙型肝炎患者的生活质量。
Objective： To assess the quality oflife of Chronic Hepatitis B before and after the treatment of Lamivudine, to improve their quality of medical care by analyzing the relevant contributing factors. Methods： The quality of life of 150 patients with Chronic Hepatitis B were assessed by the quality of life questionnaire （SF-36）, and single and multiple stepwise regression analysis were made to evaluate factors affecting it. Results： The total mark of SF-36, marks of physical function （PF）,role-physical（RP）,mental health （MH）,social function （SF）,bodily pain （BP） and vitality（V） were significant different before and after the treatment of Lamivudine. The factors affecting the marks of SF-36 of patients were mainly focused on duration of disease, cultural atandard, financial condition, complications, jaundice and ALT. Conclusion： The quality of life of patients with Chronic Hepatitis B can be improved by the using of Lamivudine.Special attention should be payed to the relevant contributing factors.
出处
《中国临床心理学杂志》
CSCD
2005年第4期472-473,共2页
Chinese Journal of Clinical Psychology
关键词
肝炎
乙型
生活质量
拉米夫定
Chronic Hepatitis B
Quality of Life
Lamivudine
