肺癌相关分子标记物检测方法的研究进展
Advance research on detection of molecular marker correlated with lung cancer
摘要
肺癌的发生、发展和演变过程中,肿瘤抑制基因的失活、原癌基因突变的激活、杂合性的缺失以及特殊染色体区域的扩增等遗传学变化导致DNA水平的变化,后者又进一步引起细胞内RNA及蛋白质水平的改变,这些变化可以产生肺癌相关分子标记物,检测肺癌患者体内各种分子异常的分子生物学方法主要有以DNA、RNA及蛋白质为基础的3种检测方法。
出处
《吉林大学学报(医学版)》
CAS
CSCD
北大核心
2005年第6期981-984,共4页
Journal of Jilin University:Medicine Edition
基金
吉林省科技厅社会发展基金资助课题(92226000)
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