摘要
目的:研究能跨越局部最优而达全局最优的模拟退火算法,结合紫外可见及红外光谱法进行重叠峰分辨,用于多组分分析.方法:将模拟退火算法结合紫外光谱法用于复方药物V it.B四组分含量测定.结果:V it.B1,B2,B6和烟酰胺(NA)的回收率分别为100.1%,100.2%,99.9%和100.1%.结论:模拟退火算法结合紫外光谱法用于多组分复方药物的含量测定,操作简便,结果良好.
AIM： To work out simulated annealing algorithm which bypasses partial but reaches whole optimization and which is combined with ultra-violet （UV） and infrared radiation （IR） spectroscopy method to resolve overlapped peaks and to analyze multiple components. METHODS： Simulated annealing algorithm combined with UV spectroscopy was used to simultaneously determine the four contents in compound pharmaceuticals-VB. RESULTS： The recoveries of Vit. BI, 132, 136 and NA were 100.1%, 100.2%, 99.9% and 100.1% respectively. CONCLUSION： The simulated annealing algorithm combined with UV is suitable for the simultaneous determination of multi-components in compound pharmaceuticals.
出处
《第四军医大学学报》
北大核心
2005年第22期2021-2024,共4页
Journal of the Fourth Military Medical University
基金
湖南省自然科学资金资助课题(03JJY4008)
化学生物传感与计量学国家重点实验室(湖南大学)开放课题(04-10)
关键词
模拟退火算法
多元分析
光谱分析
复方药物
硫胺素
核黄素
维生素B6
烟酰胺
simulate anneal arithmetic
multivariate analysis
spectrum analysis
compound pharmaceutical products
thiamine
riboflavin
vitamin 136
niacinamide
