摘要
背景:二维超声检测技术在国内外广泛应用于检测颈动脉粥样硬化病变及血流受阻程度,也可应用于对高血压病及高血压并脑卒中患者进行颈动脉监测。目的:探讨高血压及高血压并脑卒中患者颈动脉粥样硬化的改变。设计:病例-对照分析。单位:一所市级医院的神经科。对象:选择聊城市第三人民医院2003-10/2004-09接受颈动脉超声检查的180例被试者,为门诊、住院患者及健康查体者。将180例被试者分为正常组(30例),原发性高血压组(50例)和高血压并脑卒中组(100例)。所有受试者均签署知情同意书。方法:对所有受试者采用二维超声显像多普勒脉冲检测双侧颈总动脉、颈内动脉、颈外动脉、颈动脉分叉。计算中层内膜厚度、管腔内径、斑块发生率及Crouse积分。结果:按意向处理分析,180例被试者全部进入结果分析。①颈动脉内膜增厚、斑块形成的发生率:正常组低于高血压组和高血压并脑卒中组(33.3%,68%,97%,P<0.01),软斑及出血斑在高血压并脑卒中组显著增加。②Crouse积分:正常组低于高血压组和高血压并脑卒中组(0.95±0.82,6.62±4.14,22.05±11.32,P<0.01)。③硬化斑块的好发部位:在颈总动脉及其分叉处最多,其次颈内动脉。结论:二维超声多普勒检测技术为无创性评估高血压对靶器官损害的一种有效方法,颈动脉粥样硬化分级可作为了解高血压对靶器官损害程度的方法,并为上述疾病的治疗提供可靠的依据。
BACKGROUND： Duplex sonography has been widely used for the measurement of carotid atherosclerosis and poor blood flow domestically and overseas. Moreover, it can be used for carotid monitoring in patients with hypertension and those with both hypertension and stroke.OBJECTIVE： This study was designed to investigate carotid atherosclerosis in patients with hypertension and those with both hypertension and stroke.DESIGN： It was a case-control study.SETTING： Neurology Department of Third People＇s Hospital of Liaocheng city.PARTICIPANTS： Totally 180 outpatients, inpatients and healthy individuals underwent carotid sonography in the Third People＇s hospital of Liaocheng City were recurited from October 2003 to September 2004. They were divided into 3 groups, as normal control group （30 people, N group）,primary hypertension group （50 cases, PH group） and hypertension and stroke group （100 cases, HS group）. Informed consents were obtained from all the participants.METHODS： All the participants underwent duplex-pulsed Doppler sonography for the measurement of internal carotid artery, external carotid artery and carotid bifurcation. Intima-media thickness, inner diameter, plaque occurrence and Crouse score of these arteries were calculated.occurrence rate of an increased intima-media thickness of carotid artery with an plaque formation： It was lower in N group than in PH group and HS group （33.3% ,68% ,97% ,P 〈 0.01）. ＂Soft＂plaque and plaque hemorlower in N group than in PH group and HS group （0.95±0.82,6.62±4.14,plaque： The most common location of carotid atherosclerotic disease is at the common carotid artery and the carotid bifurcation and then is the internal carotid artery.CONCLUSION： Duplex pulsed Doppler sonography is known as an effective and non-invasive technique for assessment of the damages on target organs caused by hypertension. Grading of carotid atherosclerosis can be used for the measurement of the damages on target organs caused by hypertension. Hereby, reli
出处
《中国临床康复》
CSCD
北大核心
2005年第39期153-155,共3页
Chinese Journal of Clinical Rehabilitation
