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肺气虚证患者血清IL-8、TNF的水平及临床意义 被引量:10

The Expression and Clinical Significance of TNF and IL-8 in Patients with Deficiency of Pulmonary Qi
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摘要 目的测定肺气虚证患者肺功能及细胞因子水平,为肺气虚证本质的研究提供一些依据。方法对58例老年肺气虚证患者及20例正常对照者进行肺功能、白细胞介素-8、肿瘤坏死因子测定。结果肺气虚证患者的肺功能明显低于对照组(P<0.01),而白细胞介素-8、肿瘤坏死因子均值明显高于对照组(P<0.01),不同程度肺气虚证候患者组间比较也有显著差异(P<0.01)。结论肺气虚证患者气道阻塞,肺功能下降,而白细胞介素-8、肿瘤坏死因子水平升高,两者成负相关关系,共同参与肺气虚证的慢性气道炎症反应。 Aim: To investigate the change of seruam levels of tumor necrosis factor and interleukin-8 in patients with Deficiency of Pulmonary Qi. Methods : Pulmonary function, TNF and IL-8 were detected in 58 cases of Deficiency of Pulmonary Qi and 20 cases of healthy subjects. Results: Both TNF and IL-8 were marking higher than those in controls, it had remarking difference among various grades of Deficiency of Pulmonary Qi. Conclusion: These suggest that patients of Deficiency of Pulmonary exist in obstruction in pulmonary function,but it has negative correlativity compared with the increase of levels of TNF and IL-8
出处 《浙江中医学院学报》 2005年第6期13-15,共3页 Journal of Zhejiang College of Traditional Chinese Medicine
基金 安徽省自然科学基金资助项目(NO:010431006)
关键词 肺气虚证 白细胞介素-8 肿瘤坏死因予 Deficiency of Puimonary Qi, TNF IL-8, tumer necrosis factor
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