摘要
应用聚合酶链反应（ＰＣＲ）技术检测４８１例乙肝血清学五项指标至少一项阳性血清中ＨＢＶＤＮＡ和ＨＣＶＲＮＡ，结果显示ＨＢＶＤＮＡ的检出率为９１．５％，ＨＣＶＲＮＡ的检出率为１５．４％，并提示（１）当乙肝患者血清中抗ＨＢｅ阳性甚至抗ＨＢｓ阳性时，仍有相当部分的ＨＢＶ存在且仍在复制；（２）ＨＢＶ和ＨＣＶ感染可相互增加其易感性；ＨＢｓＡｇ阳性与否与抗ＨＣＶ可能有一定关系；（３）ＰＣＲ检测ＨＢＶＤＮＡ、ＨＣＶＲＮＡ具有较高的敏感性。
HBV DNA and HCV RNA of 481 pa-tients with hepatitis B were tested by polymeraseChain reaction(PCR).The results showed that 91.5%and 15.4% of HBV DNA and HCV havebeen detected respectively.The results suggestedthat (1)HBV is duplicatin in some anti-HBe and an-ti-HBs carriers,(2)the susceptibility of HBV andHCV can be increased each other,and it is possiblethat HBsAg positive is relative to anti-HCV positive,(3)PCR can detect HBV DNA and HCV RNA inserum sensitively.
出处
《现代诊断与治疗》
CAS
1996年第2期71-72,共2页
Modern Diagnosis and Treatment
