摘要
帕金森病是一种神经节退行性疾病,主要以静止震颤,肌肉僵直和运动减少为临床症状。在其各种治疗方法中基因治疗最有望彻底治愈PD,最有发展前景。但其有效性与安全性与其所选用的载体有很大关系。本文介绍了基因治疗中常用的病毒载体以及它们的特性,并指出PD基因治疗中病毒载体的发展趋势。
parkinson＇s disease （PD） is a degenerative disease of the basal ganglia causing tremor at rest, muscle rigidity and hypokinesia. Gene therapy is most likely to cure PD completely, and the most promising one among all the treating ways. But its effectiveness and safety have a strong relationship with the vectors chosed. This article introduces some usually used virus vectors and their characteristics as well as the trend of virus vector in PD＇ s gene therapy.
出处
《华西医学》
CAS
2005年第4期797-798,共2页
West China Medical Journal
