摘要
Seven new sesquiterpenoids, namely eupatochinilides Ⅰ-Ⅶ (1-7), together with eight known compounds, euponin (8), mollisorin A (9), niveusin B (10), 8β-(4'-acetoxy-tiglyloxy)-3β-hydroxy-6Hβ,7Hα-germacra-1(10)E,4E,11(13)-trien-6,12-olide (11), eupalinifide B (12), 8β-(4'-hydroxytigloyloxy)-5-desoxy-8-desacyleuparotin (13), 3-deacetyeupalinin A (14), and 15-hydroxyleptocarpin (15), were isolated from the ethanolic extract of the whole plant of Eupatorium chinense L. Their structures and stereochemistry were established by spectroscopic methods and GIAO based ^13C NMR chemical shift calculations.
Seven new sesquiterpenoids, namely eupatochinilides Ⅰ-Ⅶ (1-7), together with eight known compounds, euponin (8), mollisorin A (9), niveusin B (10), 8β-(4'-acetoxy-tiglyloxy)-3β-hydroxy-6Hβ,7Hα-germacra-1(10)E,4E,11(13)-trien-6,12-olide (11), eupalinifide B (12), 8β-(4'-hydroxytigloyloxy)-5-desoxy-8-desacyleuparotin (13), 3-deacetyeupalinin A (14), and 15-hydroxyleptocarpin (15), were isolated from the ethanolic extract of the whole plant of Eupatorium chinense L. Their structures and stereochemistry were established by spectroscopic methods and GIAO based ^13C NMR chemical shift calculations.
基金
Project supported by the National Natural Science Foundation of China (No. 30025044) and the Foundation of the Ministry of Science and Technology of China (No. 2002CB512807).