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Seven New Sesquiterpene Lactones from Eupatorium chinense 被引量:3

Seven New Sesquiterpene Lactones from Eupatorium chinense
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摘要 Seven new sesquiterpenoids, namely eupatochinilides Ⅰ-Ⅶ (1-7), together with eight known compounds, euponin (8), mollisorin A (9), niveusin B (10), 8β-(4'-acetoxy-tiglyloxy)-3β-hydroxy-6Hβ,7Hα-germacra-1(10)E,4E,11(13)-trien-6,12-olide (11), eupalinifide B (12), 8β-(4'-hydroxytigloyloxy)-5-desoxy-8-desacyleuparotin (13), 3-deacetyeupalinin A (14), and 15-hydroxyleptocarpin (15), were isolated from the ethanolic extract of the whole plant of Eupatorium chinense L. Their structures and stereochemistry were established by spectroscopic methods and GIAO based ^13C NMR chemical shift calculations. Seven new sesquiterpenoids, namely eupatochinilides Ⅰ-Ⅶ (1-7), together with eight known compounds, euponin (8), mollisorin A (9), niveusin B (10), 8β-(4'-acetoxy-tiglyloxy)-3β-hydroxy-6Hβ,7Hα-germacra-1(10)E,4E,11(13)-trien-6,12-olide (11), eupalinifide B (12), 8β-(4'-hydroxytigloyloxy)-5-desoxy-8-desacyleuparotin (13), 3-deacetyeupalinin A (14), and 15-hydroxyleptocarpin (15), were isolated from the ethanolic extract of the whole plant of Eupatorium chinense L. Their structures and stereochemistry were established by spectroscopic methods and GIAO based ^13C NMR chemical shift calculations.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2005年第11期1530-1536,共7页 中国化学(英文版)
基金 Project supported by the National Natural Science Foundation of China (No. 30025044) and the Foundation of the Ministry of Science and Technology of China (No. 2002CB512807).
关键词 Eupatorium chinense SESQUITERPENOID eupatochinilides Ⅰ-Ⅶ gauge-independent atomic orbital quantum chemical calculation Eupatorium chinense, sesquiterpenoid, eupatochinilides Ⅰ-Ⅶ, gauge-independent atomic orbital,quantum chemical calculation
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