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缓解型血清阴性对称性滑膜炎伴凹陷性水肿综合征4例报告并文献复习

Remitted Seronegative Symmetrical Synovitis with Pitting Edema Syndrome:Report of 4 Cases and Literature Review
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摘要 目的:探讨缓解性血清阴性对称性滑膜炎伴凹陷性水肿综合征(RS3PE)的临床特点,减少漏诊和误诊.方法:回顾性分析4例RS3PE综合征患者的临床资料并复习相关文献.结果:4例均为男性,年龄53~80岁, 均表现为突发双手、足背凹陷性水肿及多关节炎;4例患者ESR、CRP均有升高,3例铁蛋白升高,4例患者RF(-).3例经激素和MTX治疗有效,1例NSAIDs有效.结论:RS3PE是一种异质性临床症候群,与风湿性,感染性,肿瘤性疾病密切相关,积极治疗可减少复发. Objective:To study the clinical manifestation of remitted seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome and reduce an omission and error of diagnosis. Methods :The symptomes ,signs ,laboratory characteristic of 4 patients with RS3PE syndrom were retrospectively studied and the related literatures were reviewed. Results:All the patients were males, 53- 80 years in age;the main clinical features of the 4 patiens were polyarthritis and acute onset of symmetrical edematin both hands and both feet;the values of ESR,CRP were significantly higher in 4cases,and FERRITIN were higer in 3 cases;RF were negative in 4 cases. The three of the four patients showed better responses after the treatment of MTX and corticosteroids,and one patient was showed better responses to NSAIDS. Conclusion:RS3PE syndrome is a beterogeneous syndrome,and is associated with different rheumatologic ,neoplastic,or infectious diseases. It will be less recurrent by treating activily.
出处 《中国误诊学杂志》 CAS 2005年第15期2815-2817,共3页 Chinese Journal of Misdiagnostics
关键词 滑膜炎/并发症 水肿 风湿性疾病/并发症 Synovitis/complications Edema Rheumatic diseases/complications
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参考文献10

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二级参考文献26

  • 1张江林,黄烽.缓解性血清阴性对称性滑膜炎伴凹陷性水肿综合征1例报告[J].军医进修学院学报,1995,16(1):56-56. 被引量:3
  • 2张妍 耿纪录 刘振平 等.RS3PE综合征一例[J].中华老年医学杂志,1997,16:185-185. 被引量:1
  • 3McCarty DJ, O' dffy JD, Pearson L, et al. Remitting seronegative symmetrical synovitis with pitting edema, RS3PE syndrome. JAMA,1985,254 : 2763 - 2767. 被引量:1
  • 4Olive A, del Blanco J, Ports M, et al. The clinical spectrum of remitting seronegative symmetrical synovitis with pitting edema. The Catalan group for the study of RS3PE. J Rheumatol, 1997,24:333-336. 被引量:1
  • 5Healey LA. RS3PE syndrome. J Rheumatol, 1990,17:414. 被引量:1
  • 6Pariser KM, Canoso JJ. Remitting, semnegative, (A) symmetrical synovitis with pitting edema-two cases of RS3PE syndrome. J Rheumatol, 1991,18 : 1260-1262. 被引量:1
  • 7Torres A, Cuende E, DePablos M, et al. Remitting seronegative symmetrical synovitis with pitting edema associated with subcutaneous streptobacillus moniliforrnis abscess. J Rheumatol, 2001,28 : 1696-1698. 被引量:1
  • 8Finnell JA, Cuesta IA. Remitting seronegative symmetrical synovitis with pitting edema (RS3PE)syndrome: a review of the literature and a report of three cases. J Foot Ankle Surg,2000,39:189-193. 被引量:1
  • 9Cantini F, Salvarani C, Olivieri I, et al. Remitting seronegative symmetrical synovitls with pitting edema (RS3PE) syndrome: a prospective follow up and magnetic resonance imaging study. Ann Rheum Dis, 1999,58 : 230-236. 被引量:1
  • 10Sibilia J, Friess S, Schaeverbeke T, et al. Remitting seronegative symmetrical synovitis with pitting edema (RS3PE):a form of paraneoplastic polyarthritis? J Rheumatol, 1999,26:115-120. 被引量:1

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