摘要
目的:探讨充血性心力衰竭(CHF)患者血浆内皮素(ET)和血管紧张素Ⅱ(AngⅡ)含量与CHF程度的关系。方法:46例CHF患者作为观察组,46例健康人为正常对照组。入选者均于清晨空腹采血,用放射免疫法测定ET 和Ang Ⅱ含量,并进行比较。结果:CHF患者血浆ET、AngⅡ含量明显高于正常对照组(P<0.001),且箍着心功能级数的升高,二者的含量也逐步增加(P<0.001)。结论:心力衰竭患者血浆内皮素和血管紧张素Ⅱ含量明显增加, 且与心力衰竭的程度密切相关。
Objective： To study and the correlation between severity of congestive heart failure （CHF） and content of plasma endothelin （ET）, plasma endothelin （Ang Ⅱ）. Methods： A total of 46 CHF patients were designed to survey group and 46 normal persons were designed to control group. All blood samples were collected to measure the levels of ET and Ang Ⅱ. Results： The levels of ET [134.6±47. 4 （μg/L） land Ang Ⅱ[223. 6±94. 8 （μg/L） ] of CHF patients were significantly higher than those of control group [80. 21±17.42 （μg/L）], [94. 18±34. 28 （μg/L）] （P〈0. 001 all）. The CHF severity more was, the content of ET, Ang Ⅱ more higher was （P〈0. 001）. Conclusion： There is a close relationship between CHF severity and ET, AngⅡ.
出处
《心血管康复医学杂志》
CAS
2005年第5期448-449,共2页
Chinese Journal of Cardiovascular Rehabilitation Medicine
