摘要
目的探讨阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)患者不同体重指数(BMI)与睡眠结构和呼吸紊乱的关系。方法经多导睡眠仪监测确诊为OSAHS的患者100例,比较BMI<25kg/m2(正常)、25≤BMI<30kg/m2(超重)和BMI≥30kg/m2(肥胖)三组患者的睡眠结构和呼吸紊乱指标。结果不同BMI组的OSAHS患者,其觉醒时间、觉醒指数、快速动眼睡眠(REM)、REM/总睡眠时间(TST)%存在统计学差异(P<0.05),以BMI≥30kg/m2组的患者睡眠结构改变显著。BMI高者,呼吸暂停低通气指数、呼吸紊乱最长时间显著增加,夜间基础氧饱和度、最低氧饱和度显著下降,氧饱和度低于90%时间及占总睡眠时间延长,呼吸暂停低通气指数(AHI)和呼吸紊乱最长时间(BDLon)升高(P<0.05)。结论不同BMI对OSAHS患者睡眠结构、AHI、BDLon和动脉血氧饱和度的影响不同。
Objective Tu explore the relationship between body mass index (BMI) ,sleep structure and respiratory disturbanees of patients with obstructive sleep apnea/hypopnea syndrome( OSAHS). Methods One hundred patients with OSAHS confirmed hy, plysommogram(PSG) were enrolled. The sleep and respiratory parameters were recurded and compared among the patients with different BMI, ie, BMI 〈 25 kg/m^2, 25 ≤ BMI 〈 30 kg/m^2 and BMI/〉 30 kg/m^2. Results The arousal period, arousal index, rapid eye inurement(REM) period, REM/total sleep time% were significantly different among those with different BMI( P 〈 0.05) .The disturbances of sleep structure were nmst signifieant in those of BMI≥30 kg/m^2. Apnea hypopnea index(AHI), the longest time of breathing disorder and arterial oxygen saturation in sleeping time were significantly different among OSAHS patients with different BMI( P 〈 0.05 ). Conclusion BMI is an important factor related to disturbances of sleep structure, AHI and arterial oxygen saturation in patients with OSAHS.
出处
《中国呼吸与危重监护杂志》
CAS
2005年第5期362-364,共3页
Chinese Journal of Respiratory and Critical Care Medicine