摘要
目的:探讨儿童注意缺陷多动障碍(ADHD)的病因及抗病毒药物治疗。方法:取201份ADHD患儿血清,用ELISA法检测。对HCMV-IgM抗体阳性者停用其他药物及针刺治疗,改用抗人巨细胞病毒药物治疗3￣7个疗程,检测不同疗程患儿血清中HCMV-IgM抗体。结果:经ELISA法测201例ADHD病儿中,有192例HCMV-IgM抗体阳性,阳性率95.5%(192/201)。用抗人巨细胞病毒药物治疗后,患儿症状和体征逐渐好转与消失。在血清中HCMV-IgM抗体检测转阴后,停止抗病毒药物治疗,经家访或信访10个月至5年,无1例复发。结论:ADHD与人巨细胞病毒感染有关,抗人巨细胞病毒药物治疗有效。
Objective： To investigate the primary cause of the children with attention deficit hyperactivity disorder （ADHD） and its therapy. Methods： 201 serum specimens of clinically diagnosed children with ADHD were tested for HCMV-IgM with ELISA, 192 of which showed positive. After being stopped the routine medicines and acupuncture treatments, all the ADHD patients were treated only with anti-HCMV drugs. During 3 - 7 courses of anti-virus therapy, their serum HCMV-IgM antibody titers were decreased and became negative gradually. Results： Following the anti-HCMV therapy, symptoms and signs of the patients gradually subsided, accompanied with the disappearance of HCMV-IgM antibodies, Then the specific therapy were stopped and further observations were held for 2 - 5 years with no recurrence. Conclusion： There was specific causal relationship between HCMV infection and ADHD, the anti-HCMV therapy has a definite therapeutic effect in the treatment of ADHD.
出处
《儿科药学杂志》
CAS
2005年第5期1-2,5,共3页
Journal of Pediatric Pharmacy
关键词
人巨细胞病毒
ELISA
儿童
注意缺陷多动障碍
Human cytomegalovirus （HCMV）
ELISA
Children
Attention deficit hyperactivity disorder （ADHD）
