摘要
顺铂是被广泛用于治疗肿瘤的化疗首选药物。顺铂注射液是含有顺铂(5mg.ml-1)、稳定剂和增溶剂的水溶液。本文研究了顺铂注射液的光稳定性。结果表明顺铂注射液光稳定性很差,在光照下,顺铂注射液会发生光水合反应和光氧化还原反应,最终析出金属铂。
Cisplatin is widely used in chemotherapy of tumors. Cisplatin Injection is water solution of cisplatin （Smg · ml^-1） with stabilizer and solubilizer in it. The photo-stability of cisplatin injection was studied and poor photo-stability was observed. When the injection was exposed to light, photo-aquation reaction and photo-redox reaction would happen, followed by platinum precipitation.
出处
《中国药事》
CAS
2005年第10期613-614,共2页
Chinese Pharmaceutical Affairs
关键词
顺铂注射液
光稳定性
cisplatin
injection
photo- stability
