摘要
目的观察两种百白破混合制剂预防接种的不良反应情况,为推广使用新疫苗提供依据。方法对2001~2003年在枣庄市疾病预防控制中心计划免疫接种门诊分别注射全细胞吸附百白破混合制剂(DTwP)和吸附无细胞百白破混合制剂(DTaP)的2150名3个月~2岁的儿童进行局部与全身反应的观察。结果注射DTwP儿童红肿、硬结发生率(10.08%和11.21%)高于注射DTaP(4.28%和1.10%)。两种制剂首剂接种不良反应发生率较低,随着接种针次的增加,发生率也相应增加。结论DTaP接种不良反应较低,安全性能好。
Objective To observe the adverse effects of two kinds of mixed diphtheria - pertusis - tetanus vaccines ( DTwP and DTaP ) after vaccination and provide basis for popularization of new vaccines. Methods Observations were made on the local and general reactions in 2 150 infants aged from 3 months to 2 years after inoculation with DTwP and DTaP in the vaccination outpatient of Zaozhuang Municipal Center for Disease Control and Prevention during the years of 2001 - 2003. Results The occurrence rates of swelling and hard nodules in infants injected with DTwP were 10.08 % and 11.21%, respectively, higher than that of the infants injected with DtaP with the rates of 4.28% and 1.10% , The adverse reaction rates were low at first injection but it was increased along with the increasing number of injections, Conclusion DTwP is safe as the adverse reactions were low after vaccination.
出处
《中国热带医学》
CAS
2005年第8期1759-1759,1721,共2页
China Tropical Medicine
关键词
百白破制剂
接种反应
观察
Diphtheria - pertusis - tetanus vaccines
Adverse reaction
Observation