摘要
目的探讨双探头18F-FDG显像对原发不明转移瘤(UPT)的诊断价值。方法应用双探头18F-FDG显像检查70例UPT患者,并根据FDG浓聚诊断原发灶。结果根据FDG显像阳性诊断为原发灶58例,其中肺癌42例,全部患者均经病理证实。原发灶诊断符合率为82.9%,以肺癌最常见。FDG显像阴性12例(17.1%),进一步检查诊断原发灶5例,随访中诊断原发灶1例,未能诊断原发灶6例。结论双探头18F-FDG显像诊断UPT原发灶是一种简便、快速、无创、灵敏的方法。原发灶以肺癌最常见。FDG显像原发灶诊断符合率达80%以上,可作为UPT的首选诊断方法。
Objective To investigate the diagnostic value of dual-head ^18 F-fluorodeoxyglucose ( ^18 F- FDG) imaging in metastatic lesion with unknown primary turnout ( UPT). Methods Seventy patients with UPT underwent dual-head ^18F-FDG imaging after iv ^18SF-FDG 1. 85 MBq/kg. The primary turnout was diagnosed according to the FDG uptake and T/N value. Results Of the 70 patients, the primary turnout was identified by positive FDG imaging and finally confirmed pathologically in 58 patients (82.9%) , and 12 patients had a negative FDG imaging ( 17. 1% ). Forty-two of the 58 positive patients were found to have lung cancer (72.4%). Among the 12 negative patients, their primary turnout was then identified by other diagnostic procedures in 5 patients (41.7%) , in 1 patlent,the primary, site was detected during follow-up, however, the primary tumour was never detected in the rest 6 patients. Conclusion Dual-probe ^18SF-FDG imaging is a simple, quick, non-invasive and sensitive technique with an accuracy over 80% in the diagnosis of unknown primary turnout. The lung is found to be the most frequent primary site. Dual-probe ^18F-FDG imaging can be recommended as the first diagnostie choice for UPT.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2005年第9期565-566,共2页
Chinese Journal of Oncology