摘要
目的了解糖尿病足部溃疡全身综合治疗的同时结合溃疡局部外敷黄芪提取液的临床效果。方法在全身系统综合治疗的基础上,以生理盐水加胰岛素(对照组)作对照,观察黄芪提取液加适量胰岛素(治疗组)持续外敷后肉芽初现时间(GT),溃疡愈合时间(HT),截肢(趾)率和死亡率的高低。结果①治疗组相应的GT和HT均显著短于对照组(均P<0.05);②75例治疗组患者中截肢(趾)者9例,占12.0%,死亡2例,占2.7%;对照组67患者中截肢或趾者25例,占37.3%,死亡7例,占10.4%,两组间截肢率存在有显著差异(P<0.05)。结论黄芪提取液外敷对糖尿病足部溃疡有治疗效果,可显著缩短溃疡愈合时间,减低截肢率。
Objective To inquire the treatment effect of liquor extraction from astragalus membranaceus for external application on diabetic foot ulcers and system treatment. Methods As the control of the 67 patients being treated by a mixed liquor of normal salt and insulin for external application ( control group) , on the basis of system treatment and local debridement on 75 patients with class 2 diabetic foot ulcers (Wagnar criteria) , the time of granulation arising (GT) ,the time of healing up (HT), the amputation rate and mortalitv were observed after using a mixed liquor of astragalus membranaceus and insulin for external application( treatment group). Results The GT and HT in treatment group are shorter significatly than those in control group ( P 〈0.05, or P 〈0.01 ),and the amputation rate in treatment group are lower significantly than those in control group( P 〈 0.05 ). There is no difference of mortality between two groups. Conclusion the liquor extraction from astragalus membranaceus for external application is more effective to help the diabetic foot ulcers heal.it can shorten the GT and the HT and reduce the amputaion rate.
出处
《临床医学》
CAS
2005年第10期1-2,共2页
Clinical Medicine
基金
广州市卫生局科研基金资助(穗卫中2000-13)
广东省中药局科研立项(粤中医2001-14)