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红毛五加多糖对体外正常人T淋巴细胞转化增殖的促进作用 被引量:6

Accelerating Effect of Polysaccharides Acanthopanax Giraldii Harms on the Transform and Proliferation of Human T Lymphocytes in vitro
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摘要 目的:研究红毛五加多糖对体外正常人外周血淋巴细胞活性的影响。方法:采用MTT比色法监测正常人外周血T 淋巴细胞活性。结果:AGP1,AGP2 and AGP3组OD值分别是0.80±0.03、0.73±0.01 and 0.67±0.02,AGP1、AGP2纽与对照组相比有统计学差异(P<0.05)。结论:红毛五加多糖对体外PHA诱导的正常人外周血T淋巴细胞的增殖有促进作用(P <0.05),可能是一种免疫增强剂。 Objective: To study the accelerating effect of polysaccharides acanthopanax giraldii harms on the transform and proliferation of healthy human T lymphocytes of peripheral blood in vitro. Method: MTT colorimetry method was used to determine the activity of T lymphocytes of peripheral blood from healthy subjects. Result : OD value in groups AGPl , AGP2 and AGP3 were 0.80 ± 0.03, 0.73 ± 0.01 and 0.67 ± 0.02, respectively. Compared with the controlled group, there were statistical significance differences of OD value (P 〈 0.05 ) in groups AGP1 and AGP2. Conclusion: AGP can significantly accelerate the transform and proliferation of the healthy human peripheral blood T lymphocytes in vitro induced by PHA ( P 〈 0.05 ) and it may be an immunity accelerating agent.
出处 《中国药师》 CAS 2005年第10期814-816,共3页 China Pharmacist
基金 江苏省徐州市社会科技发展计划项目(编号X2001052)
关键词 红毛五加多糖 T淋巴细胞 增殖 AGP Lymphocytes Proliferation Promotion
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