摘要
目的研究妊娠巨幼红细胞性贫血成因,为预防和治疗妊娠期巨幼红细胞性贫血提供实验依据。方法检测了580例妊娠巨幼红细胞贫血患者WBC、Hb、RBC、HCT、MCV、MCH、MCHC、RDW、PLT等全血细胞指标及患者骨髓细胞分析检查。结果①妊娠巨幼红细胞贫血患者180例Hb低于45g/L,220例白细胞低于3.2×109/L,253例血小板低于62×109/L,398例MCV和MCH低于正常值。②骨髓表现为增生明显活跃或增生极度活跃;可见典型巨幼红细胞及粒系统巨幼变。结论孕妇产前定期检查是必要的。而对引起巨幼红细胞贫血的原因预防更重要。发现妊娠巨幼红细胞贫血,尽早应用叶酸治疗,均可取得好的疗效。
Objective To study the causes of gestational megaloblastic anemia（MgA）, and afford laboratory evidences for preventing and treating gestational MgA. Methods The complete blood cell indexes of 580 MgA patients were analysed, including WBC, Hb, RBC, HCT, MCV, MCH, MCHC, RDW, PLT and so on. The myelograms of these patients were also statistic analysed. Results Among the 580 patients, there are 180 patients whose hemoglobin are below 45g/L, 220 patients whose WBC are below 3.2×10^9/L, 253 patients whose PLT are below 62 × 10^9/L, 398 patients whose MCV and MCH are below reference ranges. In addition, all their myelograms are hypereellularity or extreme hypereellularity. Typical megaloblasts and megaloblastic granulocytes are common in the bone marrows. Conclusion It＇ s necessary for pregnant women to take regular examines before parturition, especially in preventing MgA. If there is a defnnte diagnosis of MgA, folic-acid treatment will result in satisfying curative effect if be used as early as possibleo
出处
《中国血液流变学杂志》
CAS
2005年第3期460-461,共2页
Chinese Journal of Hemorheology
关键词
妊娠
巨幼红细胞贫血
gestation
megaloblastic anemia
