摘要
以常用中草药夏枯草为原料,建立了夏枯草中有效成分熊果酸的最佳提取条件:以90%的乙醇为提取剂,在85℃提取2次,提取时间分别为2 h和1 h,夏枯草与乙醇的最佳固液比(质量∶体积)为(1∶8)^(1∶10)。提取物浓缩后的浸膏用石油醚洗涤3次,每次加入量约为浸膏量的8倍,洗涤后的浸膏用乙醇溶解,最后用活性炭脱色2次,重结晶得到白色熊果酸晶体,熔点为280~284℃,采用红外光谱法和HPLC对晶体进行了表征,产品的纯度达91.2%。
The optimum extraction conditions of ursolie acid from selfheal are found . With 90 % ethanol, the extractiori of ursolic acid from the herbal medicine is conducted twice at 80 ℃ for 2 h and 1 h, respectively. The ratio of the mass of solid ＇to ethanol volume is in the range of （ 1 ： 8）. - （ 1 ： 10）. After concentration, the crude residue is purified 3 times with petroleum ether, then dissolved in ethanol and deeolorized twice with activated charcoal. The melting point of the product is 280 - 284℃ and its characterization is done with IR and HPLC. The purity is 91.2% for the final product.
出处
《化学世界》
CAS
CSCD
北大核心
2005年第10期617-620,共4页
Chemical World
关键词
夏枯草
熊果酸
提取
表征
selfheal
ursolic acid
extraction
characterization
