摘要
目的:探讨益肺健脾中药对慢性阻塞性肺疾病患者肺功能和营养状况的调节作用。方法:①选择2000-01/10呼吸科门诊就诊的缓解期慢性阻塞性肺疾病患者20例,男18例,女2例。均自愿参加各项指标检测。按理想体质量百分比将患者分为2组:理想体质量百分比<90%为营养不良组8例,理想体质量百分比≥90%为营养正常组12例。根据病情程度将患者分为3组:第1秒用力呼气量占预计值百分比≥70%为轻度组3例,50%<第1秒用力呼气量占预计值百分比≤69%为中度组10例,第1秒用力呼气量占预计值百分比≤50%为重度组7例。②给予慢性阻塞性肺疾病患者益肺健脾中药(黄芪30g,党参15g,白术15g,茯苓15g,防风10g,半夏15g,陈皮10g,地龙8g,款冬花10g,甘草10g。偏于中阳虚者加干姜6g;肺金郁热者加黄芩10g;痰浊偏甚者加白芥子10g;气逆喘甚者加苏子10g,旋复花10g),1剂/d,水煎取汁,分2次服用,疗程8周。③用肺功能仪测定第1秒用力呼气量占预计值百分比、第1秒用力呼气量占用力肺活量百分比。根据受试者身高、年龄查得理想体质量,求出实际体质量占理想体质量百分比。④计量结果差异性比较采用t检验。结果:比较不同病情程度患者营养状况和肺功能时轻度组患者样本例数少(3例)不纳入结果分析。①第1秒用力呼气量占预计值百分比、第1秒用力呼气量占用力肺活量百分比和理想体质量百分比:益肺健脾中药治疗后明显高于治疗前犤(63.6±14.7)%,(61.5±6.6)%,(96.2±13.8)%;(55.2±14.8)%,(57.5±5.9)%,(94.4±14.6)%,t=5.9,5.8,7.8,P<0.01犦;营养不良组和营养正常组治疗后明显高于治疗前(t=2.7～9.6,P<0.05～0.01);中度组和重度组治疗后明显高于治疗前(t=2.5～6.7,P<0.05～0.01)。②理想体质量百分比:营养正常组治疗前和治疗后明显高于营养不良组治疗前和治疗后(t=6.7,6.7,P<0.01)。③第1秒用力呼气量占预计值百分比和第1秒用力呼气量�
AIM： To explore the adjustable effects of Yifei Jianpi herbs on the pulmonary function and nutritional status in patients with chronic obstructive pulmonary disease （COPD）, METHODS： ① Twenty patients with COPD in the remission phase, who were treated in the out-patient clinic of Department of Respiratory Medicine from January to October 2000, were selected, including 18 males and 2 females. They all took part in the examination of every index voluntarily. According to the ideal percentage of body mass, the patients were divided into two groups： those whose percentage of ideal body mass 〈 90% belonged to dystrophy group with 8 cases, and those whose percentage of ideal body mass ≥90% belonged to normal nutrition group with 12 cases. According to the severity of patient＇s condition, the patients were divided into 3 groups： forced expiratory volume in first second （FEV1）/anticipated value ≥170% was mild group with 3 cases, 50% 〈 FEV1/anticipated value ≤ 69% as moderate group with 10 cases, FEV1/anticipated value ≤ 50% as severe group with 7 cases. ② The Yifei Jianpi herbs （30 g membranous milkvetch root, 15 g tangshen, 15 g largehead atractylodes rhizome, 15 g India bread, 10 g divaricate saposhnikovia root, 15 g pinellia tuber, 10 g tangerine peel, 8 g earth-worm, 10 g common colts foot flower, 10 g liquorice root; Adding 6 g dried ginger to those who had week middle-jiao yang; adding 10 g baikal skullcap root to those who had lung-yin and stagnated heat; adding to 10 g white mustard seed to those who had muddy sputum; adding 10 g common perilla fruit and 10 g inula flower to those had dyspnea;） were given to the patients with COPD, once a day, decocted in water and gained the juice, taken at twice for 8 weeks. ③ The percentages of FEV1/anticipated value and FEV1/forced vital capacity （FVC） were detected with the pulmonary function meter. According to the height and age of the patients, the ideal body mass was searched to gain the percentage of actual body mass/ideal body
出处
《中国临床康复》
CSCD
北大核心
2005年第31期141-143,共3页
Chinese Journal of Clinical Rehabilitation
