摘要
目的:调查2型糖尿病患者参加营养教育情况,分析膳食血糖生成指数与血清生物化学指标的相关性。方法:①选择中山大学附属第二医院糖尿病病友之家2001年登记名单中的106例2型糖尿病患者,年龄30～70岁。均对调查的测定项目知情同意。②对患者既往参加糖尿病营养教育的主要内容进行调查,分为糖尿病基本知识、食物交换份法和食物血糖生成指数等3个问卷。同时进行相关营养知识调查,每张问卷10个题目,答对1题计1分,答错或不知道计0分,不扣分,满分为10分。膳食调查采用24h询问法,连续3d,详细记录每例的膳食食物种类和数量。计算早、中、晚三餐血糖生成指数。③血糖测定采用葡萄糖氧化酶法,总胆固醇和三酰甘油测定采用酶比色法,低密度脂蛋白胆固醇测定采用聚乙烯硫酸沉淀法,高密度脂蛋白胆固醇测定采用磷钨酸-酶沉淀法。应用稳态模型评估法计算胰岛素抵抗指数(空腹血糖×空腹胰岛素/22.5)。④组间比较应用方差分析和t检验。计数资料采用χ2检验。以三餐血糖生成指数与空腹血糖、餐后2h血糖、糖化血红蛋白、三酰甘油、总胆固醇、低密度脂蛋白胆固醇、胰岛素抵抗和高密度脂蛋白胆固醇变量,进行单因素相关分析。结果:糖尿病患者106例均完成问卷调查并进入结果分析。①参加营养教育情况和营养知识得分:参加1次及以上血糖生成指数知识营养教育的例次百分比明显低于参加糖尿病营养基本知识和食物交换份法知识教育者(4.7%,89.6%,83.0%,χ2=56.1374,47.3086,P<0.01)。食物血糖生成指数知识和食物交换份知识得分明显低于糖尿病营养基本知识得分[(2.14±1.08),(2.37±1.21),(5.11±2.34)分,t=9.2910,P<0.01];与食物交换份知识得分相近[(2.37±1.21)分,P>0.05]。②各餐血糖生成指数与生物化学检验结果相关性:早、午、晚三餐血糖生成指数与空腹血糖、餐后2h血糖�
AIM： To investigate status of nutritional knowledge and analyze the correlation of glycemic index and serum biochemical index in patients with type 2 diabetes mellitus. METHODS： ① 106 patients with type 2 diabetes, aged 30-70 years old, who registered in the Family of Diabetes Patients, Second Affiliated Hospital, Sun Yat-sen University in 2001, were selected. They all knew the program and agreed. ② The main content of education on diabetes nutrition before was investigated, including 3 questionnaires： Essential knowledge of diabetes, food exchange portion and food glycemic index. Meanwhile, related nutritional knowledge was investigated, 10 topics in every questionnaire, 1 point for one right answer, wrong answer or unknown answer as 0 point, did not deduct, full mark as 10 points. The food investigation was conducted with 24 hours inquiry for 3 days, and every food kind and quantity were recorded morning, afternoon and evening was in detail. The glycemic index in the calculated. ③ The blood sugar was detected with glucose oxidase method; The total cholesterol and triacylglycerol were detected with the triglycerides kit; the low density lipoprotein cholesterol was detected with the polyvinyl sulfuric acid sedimentation; The high density lipoprotein cholesterol was detected with the phosphorum tungstic acid-enzyme sedimentation. The insulin resistance index （IRI） （fasting glucose x fasting insulin/22.5） was calculated with homeostasis model assessment （HOMA）. ④ Using analysis of variance and t-test to perform the comparison among groups： The enumeration data were measured with the x^2 test. The glycemic index in three meals, fasting blood sugar, blood sugar at 2 hours after meal, glycated ferrohemoglobin, triacylglycerol, total cholesterol, low density lipoprotein cholesterol, insulin resistance and high density lipoprotein cholesterol variance were used to perform the single factor related analysis. RESULTS： 106 patients with diabetes were all conducted the questionnaire and involve
出处
《中国临床康复》
CSCD
北大核心
2005年第31期37-39,共3页
Chinese Journal of Clinical Rehabilitation
基金
中国预防医学科学院达能营养中心膳食营养研究与宣教基金(DIC200313)~~
