摘要
维生素E琥珀酸酯(VES)较维生素E(VE)的性质稳定,在医药和化妆品等领域得到了更广泛的应用。以维生素E和琥珀酸酐为原料,丙酮为溶剂,三乙胺为催化剂反应得到了维生素E琥珀酸酯的反应液。将反应液在3℃下冷却静置10h左右,琥珀酸酐沉淀析出,回收率82.6%:0.08MPa下减压蒸馏出三乙胺和丙酮;蒸镏余液用止己烷溶解,溶液很快沉淀分层,经过滤、洗涤得到VES,回收率为82%,纯度为93%。
Compared with vitamin E （VE）, vitamin E succinate （VES） is stabler and has a wide use in medical and cosmetics fields. The reaction solution was prepared by vitamin E and succinic anhydride as resource, acetone as solvent, triethylamine as catalyst. The reaction solution was placed at 3 ~C for about ten hours and the succinic anhydride can be cemented out from the mixture, the reclaiming can reach 82.6%. Then the distillation cut of triethylamine and acetone were got in the vacuum of 0.08MPa. The residue was dissolved in hexane. The solution precipitated and separated quickly, then it was filtrated and washed; the reclaiming of VES is 82% and purity of the product is 93%.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2005年第9期320-322,共3页
Food Science
基金
武汉市科技局攻关项目(200260007172-236)
