摘要
以原甲酸三乙酯为解水试剂,以氯化铵为催化剂,由无水乙醇和丙酮缩合制得丙酮缩二乙醇。通过单因素条件实验方法考察该反应,得到了适宜的工艺条件:丙酮26g(0.45mol),原甲酸三乙酯74 g(0.5mol),乙醇75mL,氯化铵0.72g(0.0135mol),回流下反应3h,收率为77.5%。
2,2-Diethoxypropane was prepared by acetone and anhydrous alcohol under triethyl orthoformate as dehydration agent and ammonium chloride as catalyst. Effects of reaction condition on the condenstion were investigated, according to the method of single factor test. The preferably condition was that acetone 26 g （0. 45 mol）, triethyl orthofomate 74g （0.50 mol）, alcohol 75mL and ammonium chloride 0.72 g were reacted under reflux for 3 h. The yield was 77.5%.
出处
《化学反应工程与工艺》
CAS
CSCD
北大核心
2005年第4期381-384,共4页
Chemical Reaction Engineering and Technology
基金
国家自然科学基金(20376072)
关键词
丙酮缩二乙醇
原甲酸三乙酯
合成
2,2-diethoxypropane
triethyl orthoformate
synthesis
