摘要
从１９８０年１月至１９９１年１２月，对１２１例表浅性膀胱肿瘤进行回顾性研究，首次手术采用经尿道肿瘤电灼术，电切术或膀胱部分切除术，术后配合膀胱内灌药辅助治疗。其中６０例术后复发（４９．６％），术后１、２、３和５年的无瘤率分别为８６．８％、７６．８％、７３．５％和６８．６％。资料表明，初诊时呈多发者、直径大于１ｃｍ和细胞恶性分级高的肿瘤术后无瘤率分别低于单发者、直径小于１ｃｍ和细胞恶性分级低的肿瘤，有显著性差异（Ｐ＜０．０５）。术后６个月内肿瘤复发者经治疗后肿瘤再次复发的机会高。术后膀胱内灌药可以预防肿瘤复发，以灌注丝裂霉素和卡介苗效果好。
From Jan,1980 to Dec.1991,121 cases of superficial transitional cell carcinoma of bladder were reviewed for prognosis.All the patients were treated either by transurethral fulguration,resection or by partial cystectomy followed by intravesical adjuvant therapy in all.60 of the 121 patients had tumor recurrence(49.6%)and the 1,2,3,5 year tumor free rates were 86.8%,76.8%,73.5% and 68.6% respectively.Cases with multiple tumors,larger(>1cm)or high grade tumors tended to have lower tumor recurrence-free rates.Patients with tumor recurrence within 6 months tended to recur again after appropriate treatment.Intravesical instillation of MMC or BCG was believed to be effective.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1996年第5期273-275,共3页
Chinese Journal of Urology
