蛋白质组学及在鼻黏膜炎症性疾病研究中应用
摘要
蛋白质组学是后基因组时代的研究热点,研究对象是直接参与生命活动的蛋白质。本文就蛋白质组学的基本概念及意义、基本技术、发展趋势及其在鼻黏膜炎症性疾病研究中的现状及临床应用价值加以综述。
出处
《国外医学（耳鼻咽喉科学分册）》
2005年第5期298-301,共4页
Foreign Medical Sciences(Section of Otolray Ngology Foreign Medical)
基金
2003年教育部博士点基金资助项目(20030533006)
2001年湖南省自然科学基金资助项目(01JJY2092)
2001年湖南省卫生厅科研课题资助项目(2001-T48)
参考文献19
-
1Wilkins MR, Sanchez jC, Gooley AA, et al. Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it. Biotechnol Genet Eng Rev, 1996, 13: 19-50. 被引量：1
-
2Anderson NL, Anderson NG. Proteome and proteomics: new technologies, new concepts, and new words. Electrophoresis, 1998, 19 ( 11 ) :1853-1861. 被引量：1
-
3Gorg A, Obermaier C, Boguth G, et al. The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis,2000, 21(6) : 1037-1053. 被引量：1
-
4Lopez MF, Bergren K, Chemokalskaya E, et al. A comparison of silver stain and SYPRO Ruby Protein Gel Stain with respect to protein detection in two-dimensional gels and identification by peptide mass profiling. Electro-phoresis, 2000, 21(17) : 3673-3683. 被引量：1
-
5Cordwell, S j, Nouwens AS, Verrils NM, et al. Subproteomics based upon protein cellular location and relative solubilities in conjunction with composite two-dimensional gels. Electrophoresis. 2000, 21 ( 6 ) :1094-1103. 被引量：1
-
6Wildgruber R, Harder A, Obermaier C, et al. Towards higher resolution: two-dimensinal Electrophoresis of Saccharomyces cerevisiae proteins using overlapping narrow 1PGs. Electrophoresis, 2000, 21 (13) :2610-2616. 被引量：1
-
7Cusack S, Belrhali H, Brain A, et al. Small is beautiful: protein microcrystallography. Nat Struct Biol, 1998, 5 ( Suppl ) : 634-637. 被引量：1
-
8Lindahl M, Stahlbom B, Svartz j, et al. Protein patterns of human nasal and bronchoalveolar lavage fluids analyzed with two-dimensional gel electrophoresis. Electrophoresis, 1998, 19 (18) : 3222-3229. 被引量：1
-
9Lindahl M, Svartz j, Tagesson C, et al. Demonstration of different forms of the anti-inflammatory proteins lipocortin-1 and Clara cell protein-16 in human nasal and bronchoalveolar lavage fluids. Electrophoresis,1999, 20 (4-5) : 881-890. 被引量：1
-
10Lindahl M, Stahlbom B, Tagesson C, et al. Newly identified proteins in human nasal and bronchoalveolar lavage fluids: Potential biomedical and clinical applications. Electrophoresis, 1999, 20 (18) : 3670-3676. 被引量：1
二级参考文献13
-
1PandeyA,MannM.proteomics to study genes and genomes[J].Nature,2000,405:837-846. 被引量：1
-
2Mike Tyers,Matthias Mann.From gencmics to proteomics [J].Nature,2003,422(13):208-215. 被引量：1
-
3Ruedi Aebersold,Matthias Mann.Mass spectrometry-based proteomics [J].Nature,2003,422(13):198-207. 被引量：1
-
4Mark S,Boguski,Martin W,Mclntosh.Biomedieal informatics for proteomics[J].Nature,2003,422(13):233-237. 被引量：1
-
5Sauer K.The genomics and proteomics of biofilm formation[ J ].Genome Biol,2003,4(6):219. 被引量：1
-
6Sam Hanash.Disease proteomiea[J].Nature,2003,422(13):226-232. 被引量：1
-
7Li cui,Chen Zhuchu,Xiao zhiqiang,et al.Comparative proteomics analysis of human lung squamous carcinoms[J ].Biochemical and Biophysical Research ocmmunications,2003,309:253-260. 被引量：1
-
8Zhou M,Yu LR.Proteomic analysis by two-dimensional polyacrylamide gel electrophoreais [ J ].Adv Protein Chem,2003,65:57-84. 被引量：1
-
9Gorg A,Obermaier C,Boguth G,et al.The current state of two-dimensional electrophoreais with immobilized pH gradients[J].Electrophoreais,2000,21(6):1037-1053. 被引量：1
-
10Corbett JM,Dunn MJ,Posch A,et al.Positional reproducibility of protein spots in two-dimensional polyacrylamide gel electrophoresis using immobilised pH gradient soelectric focusing in the first dimension:an interlaboratory comparison [J ].Electrophoreais,1994,15(8-9):1205-1211. 被引量：1
共引文献2
-
1贺广湘,孙虹,王天生,李萃,刘火旺,陈玉.鼻息肉病与正常鼻黏膜组织的蛋白质组差异分析[J].临床耳鼻咽喉科杂志,2006,20(5):212-216. 被引量：4
-
2贺广湘,孙虹,王天生,李萃,刘火旺,陈玉.鼻息肉的2-DE图谱建立和蛋白质组学分析[J].中南大学学报（医学版）,2006,31(4):487-492. 被引量：1
-
1高雪飞,段芝华.关于蛋白质组学及其在眼科的应用[J].哈尔滨医药,2004,24(6):59-61. 被引量：1
-
2张国华,李湘平.人β-防御素及其在鼻黏膜免疫中的作用[J].国际耳鼻咽喉头颈外科杂志,2008,32(2):67-69.
-
3于文强.反义技术在造血系统疾病研究中的应用[J].陕西医学杂志,1997,26(8):481-483.
-
4宋振梅,张尚忠.蛋白质组学在消化系肿瘤标记物检测中的应用[J].国外医学（肿瘤学分册）,2004,31(11):852-855.
-
5许国铭.应加强慢性胰腺炎的研究[J].中华内科杂志,2005,44(8):562-563. 被引量：1
-
6杨汉霞,覃纲,陈隆晖.树突状细胞与鼻部炎性疾病[J].国际耳鼻咽喉头颈外科杂志,2010,34(3):162-165.
-
7徐敏敏,吴玮.辅助性T细胞17与变应性鼻炎及鼻息肉[J].国际耳鼻咽喉头颈外科杂志,2011,35(3):177-180.
-
8李悦国,张维铭.蛋白质组学在肝癌及其相关疾病研究中的应用[J].中国肿瘤临床,2005,32(16):957-960. 被引量：4
-
9杨娜,张佳,孙克巍.鼻腔恶性黑色素瘤的确诊及治疗分析[J].中国耳鼻咽喉头颈外科,2016,23(4):237-238. 被引量：11
-
10陈伟,薄隽杰.膀胱癌的光动力学治疗[J].中国激光医学杂志,2008,17(2):129-132. 被引量：2
