摘要
92例中晚期肝细胞癌在肝动脉化学栓塞(TACE)治疗前作靛氰氯(ICG)排泄试验,据15分钟滞留率(ICGR15)将患者分甲组(ICGR15<10%),乙组(ICGR15 10%～20%)和丙组(ICGR15<20%)。结果,92例肝癌患者 ICGR15平均为15.84±12.73%,其中56例(60.87%)ICGRI5>10%;76例肝功能 Child A 级患者中40例(52.63%)ICGR15>10%。在 TACE 治疗,周肝功能损害或加重发生率甲组最低,乙组次之,丙组最高(P<0.01),肝功能损害程度亦为甲组最轻,丙组最重。92例中8例(8.7%)1月内发生 TACE 相关性肝功能衰竭,其中7例 ICGR15>20%。本文结果表明,ICG 排泄试验比肝功能 Child 分级更能反映肝硬化代偿期肝癌患者肝脏储备功能,在肝癌治疗中具有指导制定个体化治疗方案临床价值。
Ninety-two patients with hepatocellular carcinoma (HCC) were under- gone indocyanine green (ICG) retention test before transcatheter hepatic artery chemoem- bolization (TACE).According to the retention rates of ICG at 15 mimutes (ICG_(R15),all the cases were divided into three groups.36 cases (ICG_(R15)<10%)were in A group.31 cases (ICG_(R15) 10%～20%)were in B group.25 cases (ICG_(R15)>20%) were in C group.The av- erage ICG_(R15) of 92 cases was 15.84±12.73%.56 of 92 cases (60.87%) were over 10%. 40 of 76 cases (52.63%) in child A were over 10%.After TACE the proportion of damage in liver function were as following.A group<B group<C group.8 of 92 cases (8.7%) oc- cured with fulminant hepatic failure.ICG_(R15) of 7 cases were over 20%.The results suggest- ed that ICG retention test is very useful in determination of liver reserved capacity and more sensitive than child's classification core in HCC.It's helpful clinically to work out a pro- grame before TACE.
出处
《介入放射学杂志》
CSCD
1996年第1期23-25,共3页
Journal of Interventional Radiology
