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IL-6对中性粒细胞在炎症中作用的影响 被引量:25

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摘要 IL-6是炎症起始阶段的一个重要致炎因子,中性粒细胞(PMN)是炎症反应的重要效应细胞,探讨IL-6对PMN在炎症中作用的影响将对了解炎症反应的机制具有重要的意义。IL-6促进PMN从骨髓释放、增强PMN的粘附和聚集、激活PMN胞内酶,并促使细胞毒性颗粒的释放,导致PMN对外来病原体的杀伤能力的增强,但同时这也可能造成自身组织细胞的炎性损伤。本文拟就有关内容作一综述。
作者 李昕 刘佳佳
出处 《国外医学(免疫学分册)》 2005年第5期277-280,共4页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
基金 四川省教育厅重点项目(2002A064)
关键词 IL-6 PMN 炎症 凋亡
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