摘要
目的:观察激素替代疗法对绝经1-3年妇女临床症状和领悟社会支持的影响,同时观察领悟社会支持与绝经后妇女的临床症状之间是否具有相关性。方法:选择2002-03/2004-09因不同的绝经综合征症状在中国医科大学附属第二临床学院妇产科就诊的自然绝经1年以上和3年以内的绝经早期妇女40例为调查对象。采用激素替代治疗,即结合雌激素(倍美力)0.3mg,1次/d,配伍安宫黄体酮2mg,1次/d,口服,同时口服碳酸钙-维生素D3(钙尔奇D)600mg,1次/d,疗程6个月。采用临床症状调查表(采用4级评分标准,0分无症状,1分症状较轻,2分症状中等程度、3分上述症状较重)观察绝经综合征症状的有无及程度。采用领悟社会支持评定量表(含12个自评项目,采用7级评分即1～7计分法,分为极不同意、很不同意,稍不同意,中立,稍同意,很同意,极同意7个级别。社会支持总分由所有条目分累计,总分84分)评定领悟社会支持度。全部病例于治疗前和治疗6个月结束时进行评定。同时对临床症状和领悟社会支持做直线相关分析,观察社会支持与临床症状是否相关。结果:40例患者均完成全部治疗,并获得治疗前后临床症状评分及领悟社会支持评分数据,全部进入结果分析。①改善绝经后妇女的绝经综合征临床症状,治疗后临床症状评分均比治疗前降低(P<0.01)。②治疗后领悟社会支持量表总评分比治疗前明显提高(48.76±8.92,35.73±7.02,P<0.01)。③绝经后妇女的领悟社会支持与失眠、烦躁易怒孤独感、肌肉关节酸痛呈明显的负相关,相关系数分别为-0.59,-0.63,-0.49,具有统计学意义(P<0.01);体力下降易疲劳也与社会支持呈负相关,相关系数为-0.37,也有统计学意义(P<0.05)。结论:①激素替代治疗不仅改善绝经后的临床症状,也能显著提高绝经后妇女领悟社会支持度。②绝经后妇女的失眠、烦躁易怒孤独感、肌肉关节酸痛症状与
AIM： To observe the influence of hormone replacement therapy on the clinical symptoms and perception of social support in 1-3 years postmenopausal women, and discuss whether there is association between their perception of social support and clinical symptoms. METHODS： Forty early postmenopausal women for more than 1 year and within 3 years, who were treated in the Department of Obstetrics and Gynecology, Second Clinical College of China Medical University between March 2002 and September 2004 for different menopausal syndrome, received hormone replacement therapy： conjugated estrogen （premarin, 0.3 rag, once a day）, combined with medroxyprogestetone acetate （2 mg, once a day, taken orally）, calcium carbonate-vitamin D3 （Caltrate D, 600 mg, once a day） was also taken orally, the course was 6 months. The existence and severity of menopausal syndrome were assessed with clinical symptoms inventory （4-grade scoring standard was adopted, 0 as no symptom, 1 point as mild symptom, 2 points as moderate symptom, 3 points as severe symptom）. The degree of perceiving social support was evaluated with the perception of social support evaluation scale （consisted of 12 self-rating items, marked with the 7-grade scoring of 1 to 7 points, which stood for extremely dissenting, very dissenting, slightly dissenting, neutral, slightly consent, very consent, extremely consent, the scores of all the items were added as the total score of social support, which was 84 points）. All the patients were evaluated before treatment and 6 months after treatment. The linear correlation between clinical symptoms and perception of social support was analyzed to observe whether there was association between social support and clinical symptoms. RESULTS： All the 40 patients fulfilled the treatment, the data of the scores of clinical symptoms and perception of social support before and after treatment were obtained and involved in the analysis of results. ① The clinical symptoms of menopausal syndrome were ameliorated in
出处
《中国临床康复》
CSCD
北大核心
2005年第24期22-24,共3页
Chinese Journal of Clinical Rehabilitation
