摘要
从藏药植物藏玄参（ＯｒｅｏｓｏｌｅｎｗａｔｔｉｉＨｏｏｋ．ｆ．）的全草中分离到４个三萜皂甙，密蒙花甙（ｍｉｍｅｎｇｏｓｉｄｅ）Ａ和Ｂ及醉鱼草甙（ｂｕｄｄｌｅｊａｓａｐｏｎｉｎ）Ｉ和Ｉａ，另外还得到阿克甙（ａｃｔｅｏｓｉｄｅ）和个羟基木犀草素－７－Ｏ－葡萄糖甙（６－ｈｙｄｒｏｘｙｌｕｔｅｏｌｉｎ－７－Ｏ－ｇｌｕｃｏｓｉｄｅ）。体外抑精实验表明，４个三萜皂甙均有较强的抑精活性，其中密蒙花甙Ａ和醉鱼草甙Ｉ的活性高于阳性对照壬苯醇醚（ＮＰ－９）。
Four triterpenoid saponins, mimengosides A and B and buddlejasaponins I and Ia were isolated from a traditional Tibetan medicinal plant, Oreosolen wattii Hook. f., together with acteoside and 6 - hydroxyluteolin -7-O-gluco side. The in vitro spermicidal activities of the four saponins were tested by a modified Sander-Cramer method. Mimengoside A and buddlejasaponin I Showed stronger activity than the positive control NP-9.
出处
《云南植物研究》
CSCD
1996年第2期229-233,共5页
Acta Botanica Yunnanica
关键词
藏玄参
玄参科
三萜皂甙
Oreosolen wattii, Scrophulariaceae, Triterpenoid saponin, Spermicidal activity
