摘要
目的了解早产儿视网膜功能发育程度。方法选取健康无眼病早产儿和足月产婴儿各25例进行闪光视网膜电图(ERG)检测,记录视杆细胞反应、视锥细胞反应及最大混合反应。对比分析两组婴儿的ERG各波反应的潜伏期、振幅以及最大反应b/a波振幅比值。结果与足月产婴儿比较,早产儿视杆细胞反应潜伏期延长(t=11.007,P=0.000),差异具有统计学意义,而振幅没有明显改变(t=1.836,P=0.069);最大反应a、b波潜伏期延长(t=2.44,P=0.010;t=10.800,P=0.000),而振幅降低(t=5.804,P=0.000;t=5.809,P=0.000),差异具有统计学意义。两组婴儿视锥细胞反应除b波振幅无明显差异外(t=0.486,P=0.628),a波潜伏期(t=4.444,P=0.000)和振幅(t=3.819,P=0.000)及b波潜伏期(t=2.850,P=0.005)差异具有统计学意义。两组间最大混合反应的b/a波振幅比值没有明显差异(t=1.142,P=0.256)。结论早产儿视网膜发育程度较足月产婴儿稍低。
Objective To investigate the degree of retinal development in preterm infants. Methods Flash electroretinography （ERG） was performed on 25 healthy preterm infants and 25 full-term ones, and the response of rod cells and cone cells and maximal mixed responses were recorded. The delitescence and amplitudes of a and b waves and the ratio of amplitudes of b-/a-wave of maximal responses were analyzed. Results Compared with the full-term infants, The delitescence of responses of rod cells in preterm infants was statistically longer （t=11. 007,P=0. 000） but without any significant changes of amplitudes （t= 1.836,P=0.069）; statistically longer delitescence （t= 2.44, P=0.010; t=10. 800 , P= 0. 000） and lower amplitude （t= 5.804,P=0.000; t=5.809,P=0.000） of a- and b- wave of maximal response were found in preterm infants group. In the response of cone cells, there were significant differences of the delitescence （t=4. 444,P=0. 000） and amplitude （t=3. 819,P=0. 000）of a wave and delitescence of b wave （t = 2. 850, P= 0. 005） between the two groups, and no statistical difference of amplitude of b-wave （t=0.486,P=0.628） between the two groups. The ratio of amplitudes of b-/a- wave of the maximal mixed response was not significantly different between the two groups （t=1. 142,P=0. 256）. Conclusions The development of retinal function is slower in preterm infants than that in full-term ones.
出处
《中华眼底病杂志》
CAS
CSCD
北大核心
2005年第5期285-287,共3页
Chinese Journal of Ocular Fundus Diseases
