摘要
目的通过计算机辅助纤维喉镜检查法(computerfiberopticpharyngocopywithMuller’smaneuver,CFPMM)检测指标与多导睡眠监测指标的相关、回归分析,进一步评价CFPMM在阻塞性睡眠呼吸暂停低通气综合征(obstructivesleepapneahypopneasyndromec,OSAHS)诊断中的应用价值。方法①对60例OSAHS患者分别行多导睡眠监测及CFPMM检查,CFPMM观察指标包括腭咽、舌咽最小截面积,矢向径与横向径比值,咽壁顺应性;②分别将CFPMM指标与睡眠呼吸暂停低通气指数(AHI)、呼吸暂停指数(AI)、最低血氧饱和度(SaO2)进行单因素相关分析,对相关系数具有显著性的变量行直线回归分析。结果①气道最大塌陷时截面积与睡眠呼吸紊乱指数呈负相关,即咽腔最大塌陷时截面积越小,则睡眠呼吸紊乱越严重:R2=0.126,咽腔最大塌陷时截面积可以解释12.6%的AHI变化;气道最大塌陷度与AHI呈正相关,即气道塌陷度(顺应性)越大,则睡眠呼吸紊乱越严重:R2=0.145,气道最大塌陷度可以解释14.5%的AHI变化;②睡眠呼吸暂停指数AI随舌咽横径及舌咽最小截面积的减小而加大,二者分别可以解释24.6%和7.7%的AI变化;③最低SaO2仅与舌咽矢径/横径比值间的相关系数具有显著性,最低SaO2随舌咽矢径与横径比值的加大而升高,舌咽矢径与横径比值可解释13%的最低SaO2的变化。结论在OSAHS的诊断中,CFPMM指标中的咽腔最大塌陷时截面积及咽腔最大塌陷度可分别在不同程度上反应AHI的高低。
OBJECTIVE Study the correlation between the anatomical abnormalities of upper airway examined by computer fiberoptic pharyngocopy with Mulleris maneuver （CFPMM） and outcomes of polysomnography （PSG）. METHODS Sixty patients with obstructive sleep apnea hypopnea syndrome （OSAHS） underwent the examination of computer fiberoptic pharyngocopy with Mulleris maneuver CFPMM and polysomnography. And analysed the relationship between the anatomical abnormalities of upper airway and serious of patients＇ sleep breath disturbance. RESULTS Diminished pharyngeal apertures and collapsibility were associated with increased rates of apnea and hypopnea index （P〈0.05）. CONCLUSION The anatomical abnormalities of UA of patients can reflect the severity of the OSAHS.
出处
《中国耳鼻咽喉头颈外科》
北大核心
2005年第8期519-522,共4页
Chinese Archives of Otolaryngology-Head and Neck Surgery
基金
国家十五科技攻关计划(2003BA712A11--17)
国家自然科学基金资助项目(30400495)
