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滑膜肉瘤的形态变异及误诊(附43例临床病理分析) 被引量:5

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摘要 目的探讨滑膜肉瘤组织学特点、免疫组织化学表达及误诊原因。方法收集滑膜肉瘤病例43例,观察HE染色切片及CK,EMA,Vimentin,等7种抗体的免疫组化染色切片。结果43例滑膜肉瘤病例中单相上皮型3例,占7.0%;单相纤维型13例,占30.2%;双向型25例,占58.1%;低分化型2例,占4.7%。免疫组化染色,单相上皮型CK、EMA100%阳性表达,Vimentin66.7%阳性表达;单相纤维型Vimentin100%阳性表达,CK、EMA阳性表达分别为38.5%和46.2%;双相型Vimentin100%阳性表达,CK、EMA阳性表达分别为64%和72%;低分化型CK、EMA及Vimentin均不表达。结论双向分化是滑膜肉瘤主要的组织学特征,其两种成分的分布比例及分化程度的不同,构成了本瘤的多样性和异质性,致使诊断困难且极易误诊。
作者 肖培 李奕
出处 《实用肿瘤学杂志》 CAS 2005年第4期278-280,共3页 Practical Oncology Journal
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参考文献7

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