摘要
雷藤氯内酯醇(T_4)的抗生育作用机理左晓春,王乃功(中国医学科学院,中国协和医科大学,药物研究所,北京100050)雷藤氯内酯醇(T4)是在分离雷公藤单体过程中得到的一个含氯单体[1],它具有雷公藤多甙的抗炎免疫抑制和抗生育活性,其抗生育活性效价约?..
Abstract Hyaluronidase activities of testes and epididymides in rats were obviously inhibited by T4po at dosage of 0.1 mg·kg-1/d for 7 weeks.T4at dosage of 0.1mg· kg-1/d for 3 weeks decreased GSH content in epididymides in rats. However,in vitro T4 at concentration of 1 0μg/ml was found to exert no effect on the content of malondialdehyde in testis or H2O2 in testis and epididymis microsornes in rats.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
1995年第5期387-389,共3页
Acta Academiae Medicinae Sinicae