摘要
采用氧氟沙星治疗急、慢性呼吸系统感染者１１０例，剂量为２００ｍｇ，２次／ｄ或３次／ｄ，口服，疗程为９±１．４ｄ。分离出致病菌１４种５４株，其中Ｇ￣－杆菌８种４４株（８１．５％），病原菌清除率为８０％，治疗总有效率为８６．４％，不良反应发生率为７．３％。结果提示氧氟沙星对Ｇ￣＋和Ｇ￣－菌都有极好的抗菌作用，可有效地用于治疗呼吸系统细菌感染性疾病。
patients with acute or chronic respiratory tract infections were treated with ofloxacin 200mg bid or 200mg tid Po. for a period of 7～ 14 days(9±1.4 days).54 strains of 14 species of bacteria were isolated among them. 44 strains of 8 species are gram-negative bacilli(81.5%).Ofloxacin is effec- tive against almost all gram-positive and gram-negative organisms with an erad- ication rate of 80%,and a total effective rate of 86.4%。The occurence rate of ADRs are 7.3%.
出处
《中国新药杂志》
CAS
CSCD
1995年第1期39-40,共2页
Chinese Journal of New Drugs
