摘要
本文报道了正常妊娠和妊高征孕妇血清和羊水碱性核糖核酸酶（ＲＮａｓｅ）活性，总蛋白、白蛋白和尿酸含量的测定结果。描述了正常妊娠孕妇羊水碱性ＲＮａｓｅ活性的变化规律，即随着妊娠的进展，其碱性ＲＮａｓｅ活性逐渐下降，３６周时最低（７６７Ｕ／Ｌ），此后逐渐回升。同时测定结果显示妊高征孕妇血清碱性ＲＮａｓｅ活性（１１０９Ｕ／Ｌ）和尿酸含量（６１５．７６５μｍｏｌ／Ｌ）较正常组显著升高，总蛋白含量显著下降（６８．９７ｇ／Ｌ）。表明妊高征孕妇肾脏的滤过与排泄功能下降，其中碱性ＲＮａｓｅ活性的变化对早期发现肾贬滤过功能的损害有一定意义。因而认为该指标有可能是一个早期诊断妊高征的指标。
bjective: The relationship between the alkalineribonuclease (RNase ) activity and pregnancy - inducedhypertension was studied. Design:The alkaline RNaseactivity and the contents of total protein,albumin anduric acid in amniotic fluid and in the maternal serum ofnormal pregnancy and PIH were observed. ReSultS:Alkaline RNase activity,the contents of total proteinand albumin decreased with the progressing of pregnancy. Uric acid content increased with the progressing of pregnancy,especially after 36 weeks pregnancy.The alkaline RNase activity and uric acid content inmaternal serum of PIH increased significantly. Conclusion:The vigorous stage of synthesizing protein of fetus may be before 36 weeks, the rising of alkalineRNase activity indicates that the glomerular filtratingfunction were damaged and it may be helpful to discover the damage of glomerular filtrating function earlier.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
1995年第4期223-224,共2页
Chinese Journal of Practical Gynecology and Obstetrics
