摘要
本文介绍66例中晚期肝癌埋置药物输注装置作肝动脉和门静脉灌注化疗的长期随访结果。治疗组29例均为不能切除的肝癌;预防组37例为姑息性肝切除术后。结果:治疗组中完全缓解2例,部分缓解11例,轻度缓解4例,无改变10例,病情发展2例,总有效率44.8%(13/29),中位生存期15月,二期切除率13.8%(4/29)。预防组中肝动脉灌注组无复发,最长已观察53月;而3例门静脉主干癌栓取出后单作门静脉灌注者均复发,术后1、2、3年生存率分别为65.7%、50%、25%。
AbstractHepatic Artery
infusion (HAI) and/or portal vein infusion (PVI) chemotherapy usingdrug delivery system for 66
patients with middle or late stage liver cancer and their long-termresults are reported. Of these,
29 patients were unresectable liver cancer (therapeuticgroup ) , 37 patients had palliative
hepatectomies (Preventive group). The results of thera-peutic group : complete regression in
two patients , partial regression in 11, mild regressionin 4, no change in 10, and progressive
disese in 2. The total effective rate was 44. 8 % (13/29) , the medium survival time was 15
months. The two stage resection rate was 13. 8% (4/29). For the preventive group, there was no
recurrence after HAI. The longe observationtime was 53 months. Recurrence was detected in all
3 patients treated with PVI after tumoremboli enucleation. The 1 ,2 ,3-yr survival rates were 65.
7% , 50%, 25% respectively.
出处
《中国普通外科杂志》
CAS
CSCD
1995年第2期65-68,共4页
China Journal of General Surgery