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新型镇静药佐匹克隆的长期毒性研究

Long-Term Toxicity Study On a Mew Hypnotic Drug Zopiclone
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摘要 本文为佐匹克隆对大鼠经口服给药为期三个月的长期毒性试验报告。通过对大鼠一般情况的观察、血液学、血液生化和组织学检查所得到的资料进行分析认为,新型镇静药佐匹克隆在10mg/kg/d剂量下,对机体各器官从形态到功能均无明显不良影响。 To study the long-term toxicity of a new Hypnotic drug zopiclone on rats. 120 rats were randomly divided into 4 groups. Three groups were given drugs in different dose, the other was served as control. After Zopiclone has been given for 3 months. We killed most of the rats and examined their blood, and the pathological changes. The results show that zopiclone is a low toxicity drug,It has no harmful effects when oral dose is under 10mg/ kg/ d.
出处 《镇江医学院学报》 1995年第3期173-174,共2页 Journal of Zhenjiang Medical College
关键词 佐匹克隆 镇静催眠药 毒性 长期毒性 Long-term toxicity Zopiclone Hypnotic drug
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