摘要
家兔33只，脲脂（500mg／kg）加氯醛糖（50mg／kg）混合静脉麻醉，三碘季铵酚制动在人工呼吸下进行实验。用电刺激延髓尾端腹外侧区（cVLM），引起血压下降。此降压作用可被电刺激对侧腓深神经（DPN）部分抑制（P＜0．001），腓深神经的调节作用在25～30min后基本消失。静脉注射纳洛酮（1．5mg／kg）或延髓头端腹外侧区（rVLM）微量注射纳洛酮（2μg溶于1μl生理盐水中）均可阻断DPN的上述抑制作用（P＜0．01，P＜0．001）。
Experiments were performed on 33 white .male rabbits anaesthetized with chloralose and urethane under artificial venti1ation. The resu1ts were as follows: (1) depressor response could be evoked by electric stimulation of caudal ventrolateral medu1la (cVLM). The inputs of deep peroneal nerve (DPN)could inhibit partly the depressor response evoked by electric stimulation of cVLM (P<0.001 ). The regulation effects of DPN disappeared in 25～30 min. (2) after iv naIoxone (1. 5mg/kg) or microinjection of naioxone into rostral ventro1ateral medulla (rVLM) (2μg/1μl NS), the inhibitory effect of DPN inputs was abolished partly(P<0. 01, P<0. 001 ).These results suggest that: (1 ) the depressor response elicited by cVLM excitation in rabbits can be regulated by inputs of DPN; (2) opiate peptide in rVLM may take part in the inhibitory effect of DPN inputs on depressor response excited by cVLM
出处
《针刺研究》
CAS
CSCD
1995年第2期12-17,共6页
Acupuncture Research
基金
浙江省卫生厅中医管理局科研基金
