摘要
本文应用扫描电镜观察了人急性早幼粒细胞白血病细胞系(HL-60)细胞中癌基因扩增的结构双微体,镜下其数量不等,范围在0～43之间,直径一段为0.5～0.8μm,约1/3为单球体。
Double minutes from a human acute promyelocytic leukemia cell line (HL-60) were examined in metaphase spreads using scanning electron microscopy. DMs are known to be sites of oncogene amplification. They appeared as two sdherical chromatin bodies interconnected by chromatin fibres. In this cell line the number of DMs varied from O/cell to 43/cell. The diameter was approximately 0.5μm-0.8μm.
出处
《中国医科大学学报》
CAS
CSCD
1989年第4期265-266,共2页
Journal of China Medical University
关键词
癌基因
双微体
扫描电镜
白血病
Double minutes
Oncogene amplification
Scanning electron microscopy
HL-60 cell line
