摘要
采用２００ｍｇ米非司酮一次顿服，２４ｈ后每隔３ｈ服用米索前列醇０．２ｍｇ的方法，对７０例１４～３３周妊娠进行了引产临床观察（Ａ组），并以６５例常规利凡诺引产作为对照组（Ｂ组）。结果：Ａ组引产成功６３例，失败７例，成功率为９０．００％，Ｂ组引产成功６２例，失败３例，成功率为９５．３８％。４８ｈ内Ａ组有９６．８３％孕妇引产成功，Ｂ组仅５９．６８％（Ｐ＜０．０１）；平均引产时间Ａ组显著短于Ｂ组，分别为３７．１９±７．１０ｈ与４５．１９±１３．５９ｈ（Ｐ＜０，０１）；Ａ组中经产妇或≤１６孕周的孕妇引产时间显著短于初产妇或＞１６孕周者（Ｐ均＜０．０１），而Ｂ组引产时间在产次、孕周方面差异无显著性。米非司酮配伍米索前列醇的服药方案用于中、晚孕引产效果与利凡诺相似，且具有引产时间短，服药方便、安全等优点，为≤１６孕周的引产提供了良好的安全引产方法。
The object of the study was to determine the efficiency of RU486 and Misopristol for termination of pregnancy. 70 wowen (group A) with 14～33 weeks'pregnancy received a single oral dose of RU486 200mg, 24 hours later, 0. 2mg misopristol was taken every 3 hours until abortion. 65 women (group B) with 14～37 weeks' pregnancy were teriminated with rivanol. Their results showed that the abortion rate was 90.00% (63/70) in group A and 95.38% (62/65) in group B.There were no statisticcally significant difference between two abortion rate (P>0.05). The duration of inducedabortion was 37.19±7.10 hours in group A compared with 45.19±13.59 hours in group B(P>0.01). In group A the duration of induced-abortion in women with multigravide or≤16weeks' pregnancy was significantly shorter than that of primigravide or >16 week' pregnancy (P<0.01), but there were no statistically difference on the two aspects, in group B. Thus, the results indicate that RU486 and Misopristol are useful for termination of 14～33 week' gestation and may replace rivanol.
出处
《现代妇产科进展》
CSCD
1995年第4期333-336,共4页
Progress in Obstetrics and Gynecology
