摘要
采用病例－对照的研究方法，对济南市区６所小学的８～１０岁血压偏高的儿童进行了４ｈ尿中血栓素Ｂ２（ＴＸＢ２）、前列环素（ＰＧＩ２，放射免疫法）排出量的对比观察。结果发现，血压偏高组儿童尿中ＴＸＢ２排出量高于血压正常组，而ＰＧＩ２排出量则低于血压正常组。单因素相关分析结果，儿童血压（收缩压）与尿中ＴＸＢ２排出量呈正相关（ｒ＝０．２２，Ｐ＜０．０５）与ＰＧＩ２的排出量呈负相关（ｒ＝－０．２５，Ｐ＜０．０５）。提示儿童血压与尿中ＴＸＢ２、ＰＧＩ２排出量有着重要关系。
The relationship between the excretion of TXB2 and PGI2 in urine and blood pressure (BP) of 8～10 years old children from six primary schools in Jinan was studied by case-control study.The results show that the average excretion of T XB2 in urine in children with high BP was higher than that in children with normal BP(p<0.05),but the excretion of PGI2 in urine was lower in the former than that in the latter.By single correlation analysis,it shows that the excretion of TXB2 in urine was significantly positively correlated with systolic blood pressure(SBP,r=0. 22,P<0. 05), but negatively correlated with(SBP,r=-0.25 P<0. 05).The results suggested that there was an important relationship between children blood pressure and the excretion of TXB2 and PGI2 in urine.
出处
《卫生研究》
CAS
CSCD
北大核心
1995年第1期48-49,共2页
Journal of Hygiene Research
关键词
儿童
血压
前列环素
血栓素
Children blood pressures
prostacylin thromboxance B_2
antioxdants
