摘要
复制成大白鼠应激性心血病模型，结果，其心肌收缩带变性，ＨＢＦＰ染色呈缺血性改变．ＧＢＨＡ染色显示心肌细胞内Ｃａ２＋沉着增多。认为这些结果对应激性心肌病和早期心肌缺血性损害的诊断有参考价值。
he purpose of this study was to investigate the pathomophologic changes of stresscardiomyopathy in rats. Stress cardiomyopathy was induced by intraperitioneal injetion ofisoproterenol(5mg/kg body wt) and /or electric stimulation 80V. 1 time/sed, 0. 1 sed/time. Theresults indicate that stredd for a short period can induce pathomorphologic changes such as contractionband necrosis of myocardial fibers,the enhanced affinity to acid fuchsin stain Which may be induced byincressed intrcellular H+. Wavy fibers seem to be no use in the diagnosis. The glycogen inmyocardial cells was decreased by isoproterenol injection, whereas it was not affected by electric stimulation alone. Both injection and stimulation could induce Ca2+ overload in myocardium. Thecytosolic Ca2+ was significiantly higher in Stimulation for 2hr after the first isoproterenol injection thanin injection alone. The GBHA method apears to be very sensitive in staling Ca2+ in myocardialcells.
出处
《苏州医学院学报》
1995年第1期6-8,共3页
Acta Academiae Medicinae Suzhou
关键词
应激性
心肌病
大白鼠
心肌
病理
形态学
Stress cardiomyopathy
catecholamine
Ca2+ overload
GBHA method (P. 6)
