摘要
采用双抗体夹心酶联免疫吸附试验（ＥＬＩＳＡ）和间接免疫荧光法检测了１４例小儿急性粒细胞性白血病和３０例正常儿童的血清可溶性白介素２受体（ｓｌＬ－２Ｒ）及Ｔ淋巴细胞亚群，结果表明：急性粒细胞性白血病血清ｓＩＬ－２Ｒ水平均显著高于对照组，差异具有显著性；Ｔ淋巴细胞亚群ＣＤ３、ＣＤ４、ＣＤ４／ＣＤ８下降，ＣＤ８升高，与对照组相比，差异显著，提示小儿急性粒细胞性白血病患者免疫功能低下易导致感染。
y using sandwitch ELISA and
indirect immuno-flurescence technique, the vaiues ofsIL-2R and
T-lymphocyte sub-population were detected in l4 children with acute
mye- locytic leukemia(AML),The serum level of sIL-2R was
significantly higher in the pa- tients than that in the control
group.C03,CD4/CD8were decreased,CD8was elevatedcompared with those of
the control group, and the difference was significant.The
resultsshowed that their immunity was poor and they were easily
infected.
关键词
白血病
髓母细胞性
T细胞
儿童
白细胞介素2
leikemia,myeloblastic
soluble interleukin 2
receptor
T-lymphocytes
chil-dren
