摘要
合成了６个６－氨基－９－（Ｎ~４′－芳香基取代乙醛缩氨基硫脲）嘌呤衍生物，并进行了抗核型多角体病毒（ＮＰＶ）活性实验。结果显示该类化合物对ＮＰＶ的抑制活性可达６７％。
Several 6-amino- 9 - (N4′ -aromatic substituted acetaldehyde thiosemicarbazone) purines have been synthesized. These new compounds were characterized by elemental analysis and IR spectra. The compounds were tested for antiviral activity in vivo in silkworm infected with Bombyx mori Nuclear Polyhedrosis Virus (NPV). The preliminary results showed that most of the compounds tested exhibited higher activity against NPV
出处
《山东医科大学学报》
1995年第3期254-256,共3页
Acta Academiae Medicinae Shandong
