摘要
本文报道了氨茶碱对小鼠胰岛移植的免疫抑制作用。作者以小鼠胰岛移植为模型,给受体鼠1%的氨茶碱灌胃,发现给药组移植胰岛的平均存活时间(MST)明显较对照长,由对照组的15.0±2.7天延长至31.9±12.6天(P<0.005),证实氨茶碱能延长移植物的存活时间。
The suppressive effect on acute transplantation rejection by aminophylline was reported. Islet transplantation in mice was used as a model. Aminophylline was given orally on 3 days before transplantation and this procedure lasted for 7 days after transplantation, It was shown that the mean survival time (MST) was significantly prolonged to 31.9±12.6 days of amtnophylline treated group in comparison with 15.0±2.7 days of the control groups.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1989年第2期102-106,共5页
Chinese Journal of Pathophysiology
关键词
氨茶碱
胰岛
免疫抑制
移植
鼠
Aminophylline
Islands of langerhans
Transplantation
Immunosupression
