摘要
用ＦⅧ相关抗原免疫组化染色定量观察４８例乳腺浸润癌。结果表明：有腋窝淋巴结转移组血管密度为每ｍｍ２１３５．４±４７．８个，无腋窝淋巴结转移组血管密度为每ｍｍ２９６．１±３１．４个，两组间的差异有显著意义（Ｐ＜０．０１）。同时血管的分布在癌组织旁每ｍｍ２１４２．４±４９．５个，在癌肿中央为每ｍｍ２９３．５±２８．６个，两组差异亦具有显著意义。结果揭示乳腺癌组织内血管生成与肿瘤的生长及腋窝淋巴结的转移关系密切。
Microvessel quantitation in 48 patients with invasive breast carcinoma was analyzed by immunohistochemistry using antibody to factor Ⅷ-related antigen. The results indicated that node-positive carcinomas demonstrated significantly higher microvessel counts than did node negative carcinomas(135.4±47. 8 and 96.1±31.4, respectively; P<0. 01)and that connective tissue adjacent to tumor showed significantly higher microvessel counts than did connective tissue of tumor center(142. 4±49. 5 and 93. 5±28.6, respectively; P<0.01). The results showed that the angiogenesis in invasive breast carcinomas correlated with the occurrence of metastasis.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
1995年第1期17-19,共3页
Chinese Journal of Clinical and Experimental Pathology
关键词
乳腺癌
微血管
定量
免疫组织化学
breast carcinoma
microvessel
quantitation
immunohistochemistry
