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OssermanⅡ_A和Ⅱ_B型重症肌无力患者呼吸肌功能的研究 被引量:2

Respiratory muscle function in the Osserman’s grade ⅡA and ⅡB Myasthenia gravis(MG)
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摘要 本文运用肺功能仪测定27例OssermanⅡA和ⅡB型MG患者呼吸肌功能,根据临床上有无呼吸困难分成两组进行统计分析,通过应用Tensilon前后的实测值及实测值与预计值差异的比较,结果显示本组患者均存在不同程度的呼吸肌无力,呼吸肌力可用胆碱脂酶抑制剂改善。 AbstractThe study was carried out in 27 cases with a wellestablished diagnosis of MG. Patients aged 13 to 63 years without lung diseases.Though none of the 21 cases in grade ⅡA andⅡB MG com- plained of dyspnea,we had found a decrease in respiratory muscle force. For example,the mean values of VC and MVV were 88.0%and 81.8%of the expected ones(P<0.05).The average VC and MVV intreased 4.6%and 1 5.3%(P<0.05)after the administration of intravenous Tensilon. The force of respiratory muscles was reduced markedly in 6 cases with grade 2 dyspnea. The mean values of VC and MVV were 66.6%and 60.3% of the expected ones(P<0.05)。The average VC and MVV increased 7.7%and 1 5.2%(P<0. 05)after the administration of in- travenous Tensilon.FVC 、IC and PIFR had the same result.These results had well demonstrated the impairment of inspiratory muscles in grade ⅡA and ⅡB MG.
出处 《临床神经病学杂志》 CAS 1995年第2期80-82,共3页 Journal of Clinical Neurology
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