摘要
目的探讨经蝶手术中鞍底硬脑膜取检对侵袭性垂体腺瘤的诊断意义。方法对40例大及巨大垂体腺瘤在经蝶手术中行鞍底硬膜取检,显微镜下观察是否有肿瘤细胞的侵袭,并与术前MRI和术中所见进行对照、分析。结果三种诊断方法得出的结果存在一定的差异,鞍底硬脑膜取检对肿瘤侵袭的检出率要高于术前MRI和术中判断。结论硬脑膜取检诊断垂体腺瘤的侵袭性相对客观;结合三种方法判断垂体腺瘤的侵袭性,对治疗方案的选择更为有利。
Objective To study the significance of sellar dura biopsy in the diagnosis of pituitary adenoma invasiveness, Methods 40 macroor huge pituitary adenomas were chosen randomly. Sellar dura were biopsied during transsphenoidal surgery, Pathological observation of tumor cell for its invasion in the dura was conducted and the observation results were compared with preoperative MRI and the intraoperative findings, Results There were significant differences in the positivity rate of invasive pituitary adenomas between the dura biopsy, preoperative MRI and the intraoperative findings. The positivity of the dura biopsy was the highest. Conclusion Dura biopsy is a relatively objective method for diagnosis of pituitary adenoma invasiveness. However, it is better to choose the treatment based on a comprehensive diagnosis.
出处
《中国微侵袭神经外科杂志》
CAS
2005年第8期358-359,共2页
Chinese Journal of Minimally Invasive Neurosurgery
基金
广东省医学科研基金项目(A2005510)
关键词
垂体肿瘤
肿瘤浸润
硬膜
病理学
外科
pituitary neoplasms
neoplasm invasiveness
dura mater
pathology, surgical
