摘要
目的:观察前列腺素E1(PGE1)治疗先天性心脏病并肺动脉高压的临床疗效。方法:将40例患者随机分为2组,对照组(20例)予常规治疗,治疗组(20例)在常规治疗基础上加用PGE1治疗。结果:治疗组临床症状、平均肺动脉压(mPAP)、动脉氧分压、动脉血氧饱和度均有显著改善。结论:PGE1治疗先天性心脏病并肺动脉高压,能显著改善临床症状,显著降低mPAP,提高动脉氧分压和动脉血氧饱和度。
Objective：To evaluate the effect of prostaglandin E1 in treatment of pulmonary hypertension with congenital heart defects. Methods：Forty patients with congenital heart disease and pulmonary hypentcnsion were randomly divided into therapeutic group and control group （20 cases）, control group were traditionally treated and the therapeutic group（20 cases）were treated with prostaglandin E1 based on the traditional therapy. Results：After administration of PGE1,the mean pulmonary artery pressurc（mPAP） was significantly reduced,the PaO2 and SaO2 were significantly increased. Conclusion： Prostaglandin E1 therapy has effect on pulmonary hypertension associated with congenital heart defect.
出处
《中国药业》
CAS
2005年第8期80-80,共1页
China Pharmaceuticals
关键词
先天性心脏病
前列腺素E1
肺动脉高压
congenital heart defect
prostaglandin E1
pulmonary hypertension
