摘要
目的研究低中心静脉压技术是否能降低肝叶切除术中的出血量,并评价这一技术对肾功能的影响。方法60例择期行肝叶切除术的病人。随机均分为对照组和低中心静脉压(LCVP)组。均采用静吸复合气管插管全麻。LCVP组通过吸入异氟醚,静注芬太尼,切肝前控制输液量,必要时微泵静注硝酸甘油,将CVP控制在4 mmHg左右。观察两组病人术中出血量、输血量、切肝前输液量和收缩压、以及术后24h肾功能变化。结果LCVP组术中出血量、输血量、切肝前输液量和收缩压均低于对照组(P<0.05)。术后24h两组病人肾功能变化无显著性差异(P>0.05)。结论低中心静脉压技术可减少肝叶切除术中的出血量及输血量,且对肾功能无明显影响。
Objective To investigate the effects of low central venous pressure （LVCP） on blood loss in liver resection and evaluate its influence on renal function. Methods Sixty patients undergoing liver resection were randomized into the placebo group （n=30） and LCVP group （n=30）. In the LCVP group, isoflurane aspiration and fentanyl injection were performed before the liver resection to control the volume of transfusion and venous injection of nitroglycerin was conducted if necessary after the resection to keep the pressure at 4 mmHg. The volume of blood loss and transfusion, the volume of transfusion before the resection, SBP and renal function were observed in both groups. Results The volume of blood loss and transfusion, the volume of transfusion before the resection and SBP were significantly lower in the LCVP group than in the placebo group （P〈0.05）. There was no marked difference in renal function between the 2 groups （P〉0.05）. Conclusions LCVP can reduce the volume of blood loss and transfusion in perioperative period of liver resection.
出处
《中华肝胆外科杂志》
CAS
CSCD
2005年第7期461-463,共3页
Chinese Journal of Hepatobiliary Surgery
